Dysraphism of the Entire Neural Tube

Craniorachischisis Totalis

  • Most severe form of neural tube defect.
  • Results from complete failure of neurulation.
  • Entire neural plate remains uncovered by mesoderm and ectoderm (skin).
  • Lesions are incompatible with life.
  • Typically leads to spontaneous abortion early in gestation.

Dysraphism of the Anterior Neural Tube

Anencephaly

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